- INCI
- Aqua, Caprylyl Glycol & Ethylhexylglycerin, Acetyl Hexapeptide-8
- CAS
- 7732-18-5, 1117-86-8, 70445-33-9, 616204-22-9
- Description
- Acetyl Hexapeptide-8 is a synthetic hexapeptide produced by solid-phase peptide synthesis (SPPS — solid-phase peptide synthesis). This technology enables precise assembly of the peptide chain from individual amino acids on a solid support, thereby guaranteeing a defined sequence and high product purity. After completion of the synthesis, N-terminal acetylation is carried out, which stabilises the molecule against enzymatic degradation and improves its percutaneous penetration. The peptide is a structural mimic of the N-terminal segment of the protein SNAP-25 (synaptosomal-associated protein 25) — a key component of the SNARE complex , which controls the release of acetylcholine at the neuromuscular junction. By competitively binding to the SNAP-25 site, Acetyl Hexapeptide-8 limits formation of the SNARE complex, reduces the intensity of muscular microcontractions and decreases the formation and deepening of dynamic expression lines . SpecPed® SC-AH8 is a pre-formulated aqueous solution from the manufacturer Spec-Chem Industry Inc. (Nanjing, China) with a certified peptide concentration of ≥ 0,05 % . The carrier — a combination of Caprylyl Glycol and Ethylhexylglycerin — simultaneously provides preservative and hydrating functions, which enables direct inclusion in the formulation without further treatment. Key benefits Competitive inhibition of the SNARE complex → temporary relaxation of facial muscles and reduction in the visibility of dynamic wrinkles (forehead, eye area, perioral area) Stimulation of type I collagen production — long-term improvement of dermal structure,full description on the product page →
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A new raw material in the field of substances that help counter skin ageing is the peptide Amino-Peptide SpecPed® (Acetyl Hexapeptide-8 0,05%). It is a raw material developed to reduce the appearance of fine lines on the skin of the face and neck. The action of Amino-Peptide SpecPed® lies in temporarily limiting the overproduction and release of the neurotransmitters that control the intensity of muscle contractions and initiate them. Thanks to Amino-Peptide SpecPed® the muscles relax temporarily, i.e. they remain in a relaxed state, so the skin above them is relaxed and smoother, which makes lines less visible.




