How to make serum with peptides?

Back 22. 01. 2025

Peptide serum for hydrating and rejuvenating your skin

 


Nowadays, with the ever-growing popularity of facial skincare products, homemade production of cosmetic products is likewise becoming a more attractive alternative. In this article, we will therefore look at a simple guide to making your own facial serum with peptides. We will examine the basic ingredients, the individual manufacturing steps and alternative raw materials. Thanks to this guide, you can create a facial serum with peptides to rejuvenate and hydrate your skin, while gaining full control over the composition and quality of the cosmetic product you use.

 

What is peptide serum made of?


Recently, peptides have become a major trend in cosmetics. Peptides have the ability to stimulate the production of collagen and elastin, thereby improving the texture of the skin and at the same time acting against wrinkles and ageing. We have prepared for you a guide to a facial serum containing Amino-Peptid SpecPed®, which helps to reduce the visible signs of skin ageing. 

 

Phase Name of raw material Content in %
A Demineralised water 83.02
A Fucocert 2.00
A Fucogel 2.00
A Fruit extract, grapefruit 1.00
A Fruit extract, blueberry 1.00
A Amino-Peptid SpecPed® 1.00
B Hyaluronic acid HMW 1.00
B Euxyl PE 9010 - preservative 0.80
B Pentylene glycol 3.00
B Glycerine 5.00
C Lactic acid 0.18
  Glass bottle with dropper, clear 1 pc


Peptide serum – how to do it?

 

1. Do not forget to disinfect all tools and packaging before starting work; you can use ethanol (ideally 70 %) in a spray.
2. Mix the raw materials of phase A together.
3. In a separate container, mix the raw materials of phase B until a thick paste is formed without any lumps of hyaluronic acid.
4. Pour the raw materials of phase A into the raw materials of phase B, stir thoroughly, the mixture will start to thicken into a gel. If you still see lumps of non-hydrated hyaluronic acid in the mixture, this is normal; cover the container with cling film and leave it to stand overnight.
5. Finally, check the pH, for example with litmus paper. Adjust it with lactic acid to a value of 4.5–5.5. Add the acid drop by drop (the indicated amount is only approximate) and after each addition mix the blend thoroughly and check the pH.

 

You can make a peptide serum for skin rejuvenation according to this guide from the Handymade workshop.


Peptide serum – a bit about the raw materials


Below we will introduce the raw materials that make up the peptide serum. Therefore, read on if you want to know how to use each raw material correctly, what its benefits are for the skin, or by what it can be replaced. In general, it applies that active raw materials such as extracts, peptide or fucogel and fucocert can be omitted from the product without significantly affecting the texture and consistency; however, you will lose the positive effects on the skin that these raw materials bring into the product. 


Demineralised water:


Demineralised water is deprived of minerals and impurities, which makes it an ideal base for cosmetic products. It is the most commonly used raw material in cosmetic formulation, because it is the solvent for many substances and provides optimal hydration for the skin without the risk of clogging pores or causing irritation. An alternative can be distilled water or hydrosols of various herbs.

 

Fucocert:


Fucocert is a natural polysaccharide obtained by fermentation of plant components. Its main advantages are its ability to improve skin hydration, reduce redness and support its regeneration. An alternative can be another hydrating natural extract, such as aloe vera.

 

Fucogel:


Fucogel is another natural polysaccharide obtained by fermentation. Its main advantage is its ability to form a protective film on the skin, which prevents moisture loss and at the same time hydrates it. An alternative to fucogel can be hyaluronic acid or glycerine.

 

Fruit extract, grapefruit:


Fruit extract from grapefruit is rich in antioxidants and vitamin C, which makes it a great raw material for cosmetics. Its main advantages include brightening the complexion, fighting free radicals and supporting collagen production. An alternative can be an extract from another fruit, such as blueberry.

 

Fruit extract, blueberry:


Fruit extract from blueberry is full of antioxidants and vitamins that help fight damage caused by free radicals and improve the overall condition of the skin. Its use in cosmetics contributes to hydration, soothing and smoothing of the skin. An alternative can be an extract from other fruits, such as from grapefruit.

 

Amino-Peptid SpecPed®:


Amino-Peptid SpecPed® (Acetyl Hexapeptide-8 0.05 %) is a natural substance developed with the aim of reducing the appearance of fine wrinkles on the face and neck. Its mechanism of action consists in temporarily limiting the production of neurotransmitters that are responsible for muscle contractions, which leads to muscle relaxation and smoothing of the skin. Amino-Peptid SpecPed® also supports the natural formation of type 1 collagen, thus becoming a gentle alternative to botox. Its advantages therefore include increased skin elasticity, smoothing of fine wrinkles and improvement of texture. An alternative can be other peptides or collagen.

 

Hyaluronic acid HMW:


Hyaluronic acid HMW has a higher molecular weight and thus, when combined with water, effectively thickens products and gives them a gel-like consistency. At the same time, it hydrates the skin by binding a large amount of water. It leaves the skin smoothed and hydrated with reduced wrinkles and fine lines. An alternative can be low molecular weight hyaluronic acid (the serum will, however, be more liquid) or other hydrating components.

 

Euxyl PE 9010 - preservative:


Euxyl PE 9010 is a broad-spectrum preservative that protects the cosmetic product against microbial growth and spoilage. Its use ensures the safety and longer shelf life of the product, and it is effective over a wide pH range. An alternative can be another preservative with similar efficacy, such as Cosgard or others. However, always check in which pH range the preservative is effective and adjust the pH of the product before adding the preservative, if the initial pH of the serum does not fall within the effective range of the preservative.

 

Pentylene glycol:


Pentylene glycol is a humectant and solvent that helps to maintain the skin’s moisture and improves the absorption of other active ingredients. It also has antimicrobial effects, thereby increasing the efficacy of preservatives. An alternative can be glycerine, which exhibits similar properties.

 

Glycerine:


Glycerine is a moisturising agent that attracts moisture into the skin and helps to keep it hydrated. In addition, it improves the texture of the skin, reduces its dryness and speeds up the hydration and dispersion of hyaluronic acid in water. An alternative can be pentylene glycol.

 

Lactic acid:


Lactic acid is a gentle exfoliant that helps to remove dead cells and stimulates skin renewal. However, in our case its ability to lower the pH of products to the value of the physiological pH of the skin was chosen. An alternative is a 50 % solution of citric acid (water acid 1:1), but the consumption of the solution of citric acid for pH adjustment will be different compared to lactic acid. 

 

Experiment with sense – warning


Before using any raw materials to produce a cosmetic product, thoroughly familiarise yourself with their properties, recommended dosage, storage conditions and safe handling. Each raw material can trigger an allergic reaction in sensitive individuals, therefore we recommend that before using the product you check whether you suffer from an allergy to any component of the raw materials or to the overall product, for example by means of a skin test.
In the case of very sensitive or acne-prone skin, or if you have other skin and health problems, we recommend consulting a medical professional before applying a new product to the skin, whether it is a homemade cosmetic product, a pure raw material or a commercially available product.
As mentioned, when experimenting with homemade recipes, it must be kept in mind that the final result can be influenced by many factors, such as humidity, temperature, quality of the raw materials and their storage.