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ACTIVE INGREDIENTS

D-Panthenol 75% W, 100 ml

Pack size100 ml500 ml1 l5 l

D-Panthenol 75% W is a liquid form of provitamin B5 , added to cosmetics for moisturisation , support of skin barrier recovery and hair conditioning. full description

AvailabilityIn stock · 440 packs
Product codeAD007_100
Batch25010801A
Best before01/2028
€6.59incl. VAT−10 %Original price €7.34€65.90/l

Lowest price in the last 30 days: €6.59

Product description

D-Panthenol 75% W is a liquid form of provitamin B5, added to cosmetics for moisturisation, support of skin barrier recovery and hair conditioning. Both skin and hair tolerate it well, which is why it ranks among the most commonly used active ingredients in formulations for dry, irritated and sensitive skin and in care for stressed hair.

The raw material contains 75 – 78.5 % D-panthenol dissolved in water. It is suitable for both rinse-off and leave-on products and is compatible with all common types of surfactants.


Key benefits

  • Moisturisation – panthenol acts as a humectant, binding water in the skin and hair shaft. Its most pronounced effect is in leave-on products, where it remains on the skin longer.
  • Skin barrier recovery – supports skin regeneration after shaving, sun exposure, frequent washing or exposure to surfactants.
  • Soothing effect – reduces the feeling of tightness and redness, which is why it has proven itself in children's cosmetics, after-shave products and intimate hygiene.
  • Hair conditioning – improves elasticity and shine of hair, eases detangling and reduces brittleness. Suitable also for colour-treated and damaged hair.
  • Broad compatibility – its non-ionic character allows it to be combined with anionic, cationic, non-ionic and amphoteric surfactants as well as with alcohol.

Use in formulation

It dissolves in water and tolerates alcohol as well. It cannot be incorporated directly into oils or anhydrous balms, where it would separate. In tonics, serums and gels it is added directly into the water phase while stirring. In emulsions it is safer to wait for the cooling phase and incorporate it below 40 °C, or alternatively add it to the finished base.

The recommended dosage is 0.5 – 5 %. The solution contains 75 % active substance, so 1 % of the raw material corresponds to approximately 0.75 % pure panthenol. As a guide: 0.5 – 1 % in tonics and shampoos, 1 – 3 % in creams and serums, up to 5 % in restorative masks and after-shave products.

It is most stable in a mildly acidic to neutral environment; the recommended pH range for the formulation is 3 – 7. At higher pH or with prolonged heating it loses stability, so add it only after cooling and adjust the pH before incorporating it.

In hair cosmetics it works in shampoos, conditioners and leave-in sprays. In rinse-off products part of the ingredient is washed away. A more noticeable result is therefore provided by a conditioner or leave-in spray, where it remains on the hair.


Suitable for products such as

  • facial creams, serums and tonics for dry, sensitive or acne-prone skin
  • after-shave and after-sun products, hand, foot and eye area creams
  • children's cosmetics and intimate hygiene products
  • shampoos, conditioners, hair masks and leave-in sprays for dry and colour-treated hair
  • shower gels and bath products, where it reduces the drying effect of surfactants
  • water-based deodorants and decorative cosmetics with a water phase, such as foundation creams

Good to know

The raw material contains water and does not contain a preservative. Every finished product with a water phase must therefore be preserved; panthenol alone does not protect against microbial growth.

It combines well with other soothing and moisturising ingredients, for example allantoin, bisabolol, hyaluronic acid or hydrolats. In combination with niacinamide it forms the basis for formulations targeted at skin barrier recovery.

For acidic formulations near the lower limit of pH 3, for example with glycolic or lactic acid, verify stability in the finished product.


Frequently asked questions

Is D-Panthenol 75% W soluble in water?
Yes, D-Panthenol 75% W dissolves in water and tolerates alcohol as well. It is added to the water phase of tonics, serums, gels and shampoos; in emulsions into the water phase or the cooling phase. In oils and anhydrous bases it does not dissolve and would separate.
When should D-Panthenol be added to a cream — hot or cold?
D-Panthenol is added to a cream only in the cooling phase, when the emulsion is below 40 °C. It tolerates brief heating, but loses stability under prolonged exposure to higher temperatures. Adding it after cooling preserves its effectiveness and does not alter the texture of the emulsion.
How much D-Panthenol should be added to a shampoo or conditioner?
For a shampoo typically 0.5 – 1 %, for a conditioner or leave-in spray 1 – 2 % of the raw material. In rinse-off products part of the ingredient is washed away, so it delivers a more pronounced conditioning effect in a conditioner or leave-in spray. When calculating dosage, bear in mind that the raw material contains 75 % active substance.
Is D-Panthenol suitable for an anhydrous lip balm?
Not directly — D-Panthenol does not dissolve in waxes and oils and would separate. In lip care it can be incorporated into products with a water phase, such as emulsified balms or gloss with a water component. For purely oil-based balms, choose oil-soluble active ingredients.
Is D-Panthenol suitable for sensitive and children's skin?
Yes, D-Panthenol is among the active ingredients with very good tolerability and is commonly used in children's cosmetics as well as intimate hygiene products. For sensitive skin, start with a lower dosage of around 1 % and test the tolerability of the finished product on a small area.
Does D-Panthenol 75% W require a safety data sheet?
No, D-Panthenol 75% W is not classified as a hazardous substance under CLP regulation, so a safety data sheet is not required for it. The raw material is not subject to hazard labelling and does not require any special protective measures beyond standard hygiene when used in routine cosmetic workshop work.

Parameters

INCI
Panthenol
CAS No.
81-13-0
EC number
201-327-3
Product color
Colorless
Country of origin
China
Appearance
Thick Liquid
Ionic character
Non-ionic
Recommended processing temperature
< 40 °C
Recommended dosage range
0,5 – 5 %
Recommended formulation pH range
3 – 7
Solubility
Water-soluble
Application type
Leave-onRinse-off
Natural Index (NI ISO 16128)
0,00
Natural Origin Index (NOI ISO 16128)
0,0
Organic content
0 %
Volume
100 ml

Product documentation

CoACertificate of Analysis
batch 24051703PDF ↓
batch 25010801PDF ↓
TDSTechnical Data Sheet
Physical parameters and processingPDF ↓
MSDSSafety Data Sheet
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From our blog
Fr.1 Oct 2026SK

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Variant: D-Panthenol 75% W, 100 ml

Great as always, it softens hair and skin.

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Greta T.21 Sept 2026IT

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A reliable and versatile ingredient. Easy to incorporate and a staple I'm always happy to have on my formulation bench.

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Nataliya20 Aug 2026DE

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Excellent quality, fast shipping, and outstanding customer service. The products are always carefully made, and whenever I have a question, the seller is very helpful and responsive. Highly recommended!

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Németh R.20 Sept 2026HU

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Variant: D-Panthenol 75% W, 100 ml

(4 reviews)