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PDRN Phycopeptide is a multi-active biotechnological complex from the microalga Chlorella vulgaris, which provides a plant-based alternative to traditional PDRN. Let’s look at what PDRN actually is, why it is mentioned so often in anti-ageing cosmetics, how this raw material differs from classic animal-derived PDRN and how to work with it in a real-life formulation.
PDRN is among the most discussed anti-ageing ingredients of recent years. In professional skincare it is associated mainly with supporting regeneration, skin firmness and a smoother appearance of fine lines. However, classic PDRN is often associated with animal origin – especially with DNA obtained from salmon sources.
PDRN Phycopeptide provides a more modern alternative: plant-based PDRN from the microalga Chlorella vulgaris, complemented by phycopeptides, amino acids and a moisturising carrier system. It is a multi-active biotechnological complex intended for more demanding anti-ageing formulations, especially for mature, sagging, tired or structurally weakened skin.
PDRN is an abbreviation for polydeoxyribonucleotides – short DNA fragments that are used in cosmetics for their potential to support a more vital, firmer and renewed appearance of the skin.
In practice this is not “miracle DNA cosmetics”, but a technologically interesting active substance that is used in formulations mainly in products focused on:
For PDRN, the molecular size is also important. Low-molecular-weight fractions are considered interesting in cosmetics precisely because they are more suitable for formulations where better availability of active ingredients in the superficial layers of the skin is expected.
The biggest difference between the two raw materials lies in their origin and the breadth of their composition. Classic PDRN is basically a single isolated fraction, whereas PDRN Phycopeptide is designed as a broader complex.
Most often associated with animal origin, especially with salmon DNA. It is used in regenerative and anti-ageing care.
However, for vegan or nature-oriented products its origin can be limiting – brands that build their communication on plant-based composition cannot rely on it.
Based on a plant origin from the microalga Chlorella vulgaris. It does not provide only the PDRN fraction itself.
It also contains chlorella extract, phycopeptides and amino acids, thanks to which it acts as a more broadly designed anti-ageing complex, not as a single isolated substance.
From a formulator’s point of view, it is also an advantage that it is a water-soluble liquid raw material that can be incorporated into serums, gels, oil-in-water emulsions as well as light cream bases.
Classic PDRN provides one fraction from an animal source. PDRN Phycopeptide provides a plant-based fraction together with phycopeptides and amino acids – a broader complex without animal origin.
PDRN Phycopeptide is not a universal additive for everything. It makes sense where you want to target skin firmness and compactness and at the same time work with plant-based composition. Here are five reasons to include it in a formula.
Suitable for formulators who want to work with a trendy PDRN raw material but prefer a plant-based and vegan-oriented origin.
The complex also contains phycopeptides from chlorella – short peptide fractions that complement the action of PDRN. The raw material is thus a more broadly designed complex, not a single isolated active substance.
Suitable for products that are meant to give the skin a smoother, firmer and more vital appearance. It fits well into formulas for the neck, décolleté, eye area and mature skin.
It is easily incorporated into the aqueous phase. It is suitable for light serums, hydrating gels, oil-in-water emulsions, gel-creams and active concentrates.
In a formulation it combines well, for example, with hyaluronic acid, niacinamide, panthenol, betaine, allantoin, gentle peptides or fermented active substances.
Thanks to its water-soluble form and anti-ageing focus, PDRN Phycopeptide is particularly suitable for:
Plant-based PDRN from the microalga Chlorella vulgaris complemented by phycopeptides, amino acids and a moisturising carrier system. A water-soluble liquid raw material for more demanding anti-ageing formulations focused on a firmer, smoother and more vital appearance of the skin.
Typical use: anti-ageing serums, firming creams for the neck and décolleté, eye serums, night masks, active concentrates.
The recommended dosage is 2 % in the finished cosmetic formulation. Since it is a water-soluble active substance, it is incorporated into the aqueous phase or into the finished emulsion during cooling.
During formulation we recommend adding it at a temperature below 40 °C in order to preserve the quality of the active fractions. This way you avoid unnecessary thermal stress on the more sensitive components of the complex.
PDRN Phycopeptide will be appreciated especially by manufacturers who want to create more modern anti-ageing products with professional depth but without heavy marketing ballast.
It is suitable for brands that want to communicate:
Practical questions from formulation practice – concentration, production phase, origin, impact on product colour and compatibility with other active substances.
The recommended dosage is 2 % in the finished cosmetic formulation. It is a water-soluble active substance that is incorporated into the aqueous phase or into the finished emulsion during cooling.
Add it to the aqueous phase or to the finished emulsion at a temperature below 40 °C. The lower temperature protects the quality of the active fractions of the complex, which is why it is not included in the hot phase of the formulation.
Yes, it is based on a plant origin from the microalga Chlorella vulgaris. That is why it is a suitable alternative to classic PDRN, which is most often obtained from salmon DNA, i.e. from an animal source.
It may. The raw material naturally has a yellowish to brownish hue, so with transparent gels and very light emulsions it can slightly shift the colour. For crystal-clear products, take this into account already at the design stage.
It combines well with hyaluronic acid, niacinamide, panthenol, betaine, allantoin, gentle peptides or fermented active substances.
Especially for mature, sagging, tired or structurally weakened skin. It fits very well into formulas for the neck, décolleté and eye area, where the goal is a firmer and more compact appearance of the skin.
PDRN Phycopeptide is an excellent choice for formulations that are meant to act modern, professional and functional. It combines the PDRN trend with plant origin from chlorella, phycopeptides and a water-soluble form suitable for serums, gels and emulsions.
It is not a simple “anti-ageing additive for everything”, but a well-thought-out biotechnological complex for products in which you want to target a firmer, smoother and more vital appearance of the skin.
When developing a firming serum, eye cream or night mask for mature skin, PDRN Phycopeptide can be exactly the plant-based active substance that gives the formula both professional depth and a communication story.
