Formula by JuanDominguez.Lab hydrating serum with goji exosomes

Back 23. 06. 2026

Hydrating serum with exosomes combines natural moisturizing factors, hyaluronic acid, oat lipids and a modern active ingredient in the form of plant exosomes from goji. The formula was prepared for us by our influencer and formulator Juan Dominguez (JuanDominguez.Lab), who is known for his well-thought-out formulations and modern approach to cosmetics.

In this formula he combined several moisturizing and regenerating components into a light emulgel serum that helps support the skin barrier, improve skin hydration and provide comfort even to sensitive skin.

The result is a gentle milky serum with a silky slip that is quickly absorbed and leaves the skin hydrated, supple and soft without unpleasant stickiness. The formula combines natural moisturizing factors (NMF), hyaluronic acid, oat lipids, bisabolol and exosomes from goji.

A great advantage of the formula is the use of the emulsifier Fluidifeel Easy, which enables formulation via low-temperature emulsification. Unlike classic emulsions, it is not necessary to heat both phases to 70–75 °C, which significantly simplifies production and helps maintain the stability of more sensitive active ingredients.

Exosome serum — low-temperature emulsification with Fluidifeel Easy emulsifier

Table of contents

About this formula

The serum is designed as a light emulgel serum with multi-level hydration. It works on several fronts at once — on the surface and in the deeper layers of the stratum corneum.

Natural moisturizing factors such as urea, inulin and panthenol provide basic hydration, hyaluronic acid binds water in the skin, oat lipids and AvenaPlex support the barrier and exosomes from goji bring a modern active component.

Why low-temperature emulsification: The emulsifier Fluidifeel Easy bridges the oil and water phase even in a cold process. You do not have to heat both phases to 70–75 °C, which simplifies manufacturing and means that more sensitive active ingredients such as exosomes are not unnecessarily exposed to heat.

Main benefits

Intensive multi-level hydration

The combination of NMF components, hyaluronic acid and polymers works on the surface and in the deeper layers of the stratum corneum.

Support and protection of the skin barrier

Oat lipids and AvenaPlex replenish barrier components and help the skin retain moisture.

Soothing of sensitive skin

Bisabolol, allantoin and panthenol provide a soothing character even for irritated skin.

Light non-greasy texture

Silky slip and fast absorption without stickiness thanks to light emollients.

Modern care with exosomes

Exosomes from goji represent a modern active ingredient in the spirit of advanced cosmetics.

Simplified manufacturing

Low-temperature emulsification eliminates the need to heat the phases to 70–75 °C and protects sensitive active ingredients.

Product properties

Product typehydrating and regenerating emulgel serum
Appearancemilky homogeneous emulsion
Batch size100 g
Target pH5.3 – 5.7
Recommended packagingtransparent airless or pump bottle

Key ingredients in the formula

The heart of the formula is several modern active and functional ingredients. You will find all of them in the range of active ingredients Handymade.sk.

Formula (100 g)

The formula is divided into seven phases (A–G) and a final pH adjustment. At the first occurrence each ingredient is linked to the product in our range.

Phase / component Amount
Phase A – Main aqueous phase
Distilled water 57.05 g
1,3-Propanediol 4.00 g
Niacinamide 3.00 g
Inulin 1.00 g
Allantoin 0.20 g
Urea (Urea USP) 2.50 g
D-Panthenol 75 % 2.50 g
Phase B – Hydration of hyaluronic acid
Vegetable glycerin 3.00 g
Distilled water 5.00 g
1,3-Propanediol 2.00 g
Hyaluronic acid (high-molecular-weight) 0.10 g
Phase C – Structure-forming polymers
Xanthan Gum Fast Dispersing 0.25 g
Pullulan DuoLux CM 0.35 g
Phase D – Oil phase
Hemisqualane 4.00 g
Isoamyl Laurate 3.00 g
Oat Lipid e 2.00 g
AvenaPlex 1.00 g
Bisabolol Alpha Natural 0.20 g
Phase E – Emulsifier
Fluidifeel Easy 4.00 g
Phase F – Exosome phase
Distilled water 3.00 g
PhytoCellTec Goji Exosomes 1.00 g
Phase G – Preservation and chelating agent
Euxyl PE 9010 0.80 g
Sodium Phytate 0.05 g
pH adjustment
Diluted lactic acid as needed
Diluted arginine solution as needed

Manufacturing procedure

1. Preparation of the workplace

Before starting work, thoroughly disinfect the work surface, beakers, stirrers, spatulas, thermometer, pH meter and final containers.

Prepare:

2. Main aqueous phase (Phase A)

Weigh into the main beaker:

Stir. Add:

Stir until completely dissolved. Then add:

Stir again. Add:

Gently heat the phase to approximately 40–50 °C so that the allantoin dissolves better.

Grind the urea in a mortar into a fine powder and add:

Stir until dissolved. After cooling below approximately 40 °C, add:

Stir to a homogeneous mixture.

3. Hydration of hyaluronic acid (Phase B)

Weigh into a separate beaker:

Stir. While stirring continuously, slowly sprinkle in:

Let it hydrate during the preparation of the other phases.

4. Addition of polymers (Phase C)

When the aqueous phase has cooled below 40 °C, slowly add:

Mix thoroughly. Then add:

Stir until fully incorporated.

5. Incorporation of hyaluronic acid

Add the hydrated mixture from Phase B to the main aqueous phase. Stir to a homogeneous consistency.

Let the mixture rest for approximately 45–60 minutes so that:

fully hydrate and form a gentle gel structure.

6. Oil phase (Phase D)

Weigh into a separate beaker:

Stir. If necessary, gently heat to 35–40 °C so that all components combine perfectly.

7. Addition of emulsifier (Phase E)

Into the fully hydrated aqueous phase add:

Mix for approximately 2–3 minutes.

8. Emulsification

Under medium-intensity stirring, slowly pour the oil phase into the aqueous phase. After complete combination:

A light milky emulsion with the consistency of an emulgel will form.

9. Preparation and addition of exosomes (Phase F)

When the emulsion has cooled below 35 °C, prepare:

Stir gently to a smooth dispersion. Add to the emulsion and stir carefully. Avoid aggressive homogenization.

10. Preservation (Phase G)

Add:

Stir.

11. Addition of Sodium Phytate

Take a small amount of the finished serum into a separate container. Disperse in it:

After complete dispersion, return the mixture back to the main batch and stir.

12. Control and adjustment of pH

Check the pH using a calibrated pH meter. Target range:

pH 5.3 – 5.7

If the pH is higher:

If the pH is lower:

Make the adjustments dropwise and after each addition stir thoroughly.

Tip: Add exosomes and hyaluronic acid in the cooling or final phase and avoid aggressive homogenization. In this way, sensitive active ingredients will retain their character and the serum will maintain a gentle gel structure.

Use

Apply 1–2 doses of serum to cleansed skin of the face, neck and décolleté. Gently massage in and then apply cream as needed.

The serum is suitable for everyday use in the morning and evening.

A well-thought-out combination of moisturizing factors, oat lipids and exosomes in one light serum — modern care that you can prepare at home.
— Juan Dominguez (JuanDominguez.Lab)

Frequently asked questions about the formula

Practical questions about the formulation — exosomes, low-temperature emulsification, choice of hyaluronic acid, pH and shelf life of the finished serum.

What are exosomes and why are they in this serum?

Exosomes are a modern active ingredient of advanced cosmetics. In this formula, PhytoCellTec Goji Exosomes are used, which are added to the cooling phase in a gentle aqueous dispersion. They give the serum technological and communication value and fit into the trend of regenerative care.

Why does this formula not need to be heated to 70–75 °C?

Thanks to the emulsifier Fluidifeel Easy, which enables low-temperature (cold process) emulsification. The oil and aqueous phase will combine even in a cold process, so it is not necessary to heat both phases to a high temperature. The manufacturing is simpler and sensitive active ingredients are not unnecessarily exposed to heat.

Which hyaluronic acid should I use?

The formula is based on high-molecular-weight hyaluronic acid (HMW), which forms a hydrating film on the skin and contributes to the gel structure of the serum. Sprinkle it in while stirring continuously and let it fully hydrate — ideally together with xanthan gum and pullulan for 45–60 minutes.

Why is Sodium Phytate added only at the end and separately?

Sodium Phytate is a chelating agent that is added in a small amount to the finished serum. First, disperse it in a small removed part of the serum and only after complete dispersion return it to the main batch. This prevents clumping and ensures even distribution.

To what pH should I adjust the serum?

The target range is pH 5.3 – 5.7, which corresponds to the physiological pH of the skin. If the pH is higher, adjust with diluted lactic acid; if it is lower, with diluted arginine solution. Make the adjustments dropwise and after each addition stir thoroughly and measure with a calibrated pH meter.

For which skin type is the serum suitable and how often should it be used?

The serum is suitable for everyday care in the morning and evening, including sensitive and irritated skin — thanks to bisabolol, allantoin, panthenol and oat components it has a soothing character. Apply 1–2 doses to cleansed skin of the face, neck and décolleté, massage in gently and apply cream as needed.

How should I store the finished serum?

Fill into an opaque airless or pump bottle, which protects the contents from light and contamination. The serum contains the preservation system Euxyl PE 9010 — however, for home manufacturing store it in a cool and dark place and monitor colour, odour and viscosity changes. For a larger batch we recommend verifying stability and microbiological safety.

Try a modern serum at home

Exosomes, oat lipids, hyaluronic acid and a low-temperature emulsifier — you can find all ingredients from this formula in the range of active ingredients Handymade.sk.

See active ingredients